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PROCESS FOR PRODUCING β-AMINO-α-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF
PROCESS FOR PRODUCING β-AMINO-α-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF
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机译:β-氨基-α-羟基羧酸的制备方法及其衍生物
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摘要
Disclosed is a process for producing β-amino-α-hydroxycarboxylic acid derivatives of general formula (2R,3S)- or (2S,3R)-N-(X,Y)-3-amino-2-hydroxy-3-phenyl-propionic acid-Z of formula (I), e.g. of (2R,3S)-3-amino-2-hydroxy-3-phenyl-propionic acid or (2R,3S)-N-benzoyl-3-amino-2-hydroxy-3-phenyl-propionic acid methylester. Compounds of type I are valuable intermediates in the total synthesis of taxols which can be used in the treatment of various forms of cancer.
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