LOCALIZED INTRAVASCULAR DELIVERY OF TFPI FOR INHIBITION OF RESTENOSIS IN RECANALIZED BLOOD VESSELS

摘要

Restenosis in recanalized blood vessels is inhibited by delivering tissue factor pathway inhibitor (TFPI) intramurally at a target site within the blood vessel. Usually TFPI is delivered using a catheter (110) having infusion ports (128) at its distal end (113). Optionally at the distal end (113) the catheter (110) is radially expanded to engage the infusion ports (128) directly against the blood vessel wall (4).