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POLYUNSATURATED FATTY ACIDS AND FATTY ACID ESTERS FREE OF STEROLS AND PHOSPHORUS COMPOUNDS

机译:不含甾醇和磷化合物的多不饱和脂肪酸和脂肪酸酯

摘要

Fatty acid esters such as those containing arachidonic acid (AA) and docosahexaenoic acid (DHA) derived from lipid mixtures and prepared with reduced levels of sterols and phosphorus. A preferred embodiment of the invention comprises extracting lipids from egg with methanol; separating lipids including sterols from insoluble egg components; submitting the methanolic solution of lipids to transesterification and subsequent neutralization to convert the lipids to methyl esters of said free fatty acids together with sterols; separating the said sterols and esters from an aqueous phase including phosphorus compounds formed in the transesterification; subjecting the said fatty acid esters and sterols to distillation to separate sterols from the fatty acid esters; and subjecting the said esters to transesterification in the presence of glycerol to produce triglycerides of said esters thereof including that of AA and DHA wherein the resulting triglycerides contain reduced quantities of sterols and phosphorus.
机译:脂肪酸酯,例如含有花生四烯酸(AA)和二十二碳六烯酸(DHA)的脂肪酸酯,它们来自脂质混合物,并以降低的甾醇和磷含量制备。本发明的一个优选实施方案包括用甲醇从鸡蛋中提取脂质。从不溶性鸡蛋成分中分离出包括固醇在内的脂质;使脂质的甲醇溶液进行酯交换和随后的中和,以将脂质与固醇一起转化为所述游离脂肪酸的甲酯;从包括在酯交换反应中形成的磷化合物的水相中分离出所述甾醇和酯;使所述脂肪酸酯和固醇经过蒸馏以从脂肪酸酯中分离出固醇;使所述酯在甘油存在下进行酯交换反应以产生所述酯的甘油三酸酯,包括AA和DHA的甘油三酸酯,其中所得甘油三酸酯含有减少量的甾醇和磷。

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