SHUTTLE VECTORS FOR THE INTRODUCTION OF DNA INTO MYCOBACTERIA AND UTILIZATION OF SUCH BACTERIA AS VACCINES

摘要

It includes at least one function replication orgin in the mycobacteria that shuttle vector, which introduces mycobacteria DNA to enter, another other functional bacterial origin of replication, enzymatic cleavage website provides insertion coding protein and allows to be expressed in mycobacteria, it is characterised in that carrier carrying gene makes anti-mycobacteria to containing heavy metal