PHARMACEUTICAL COMPOSITIONS CONTAINING A BILE SALT AND A BUFFER FOR INCREASED BIOAVAILABILITY OF AN ACTIVE COMPOUND

摘要

Compositions containing a bile salt and a buffer such as a carbonate or bicarbonate salt which is adapted to buffer the gut to a pH of from 7.5 to 9 are capable of increasing the bioavailability of an active molecule whilst minimising the toxic side effects which are generally associated with bile salts.