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AMIDES OF MONO AND BICARBOXYLIC ACIDS WITH AMINO ACIDS OR GLYCOSAMINES, SELECTIVELY ACTIVE ON THE CANNABINOID PERIPHERAL RECEPTOR
AMIDES OF MONO AND BICARBOXYLIC ACIDS WITH AMINO ACIDS OR GLYCOSAMINES, SELECTIVELY ACTIVE ON THE CANNABINOID PERIPHERAL RECEPTOR
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机译:单价和双羧酸与氨基酸或糖胺的酰胺,对大麻素外围受体具有选择性活性
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摘要
The vast number of theoretically conceivable compounds resulting from the combination of all claimed substituents in formula (I) precludes a comprehensive search. For economical reasons the search has been limited to the following compounds: R1 is a hydrocarbon radical unsubstituted or substituted by only one OH-group and having a linear chain of at least 8 carbons atoms(A); the NR2R3 group is either a linear alpha-, beta-, or gamma-, amino acid (e.g. amino acids like proline are not included), or a glycosamine residue. Despite the above limitation the search revealed too many relevant compounds. Therefore the search was further limited to compounds with NR2R3 = Glycine, beta-Alamine, gamma-amino-butyric acid, Serine- or Cysteine derivatives, or glycosamine of the following structures: (a), (b), (c). Still too many pertinent compounds where retrieved which can not all be cited in the search report. The documents cited are only an arbitrary selection and the search report has to be regarded as incomplete.
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