N-((3,4-DICHLOROPHENYL)-AMINO)-CARBONYL-2,3-DIHYDROBENZOFU- -RAN-5-SULFONAMIDE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT, METHOD OF ITS SYNTHESIS AND COMPOSITION SHOWING ANTITUMOR ACTION

摘要

FIELD: organic chemistry. SUBSTANCE: product: N-[((3,4-dichlorophenyl)-amino)-carbonyl]-2,3-dihydrobenzofu- -ran-5-sulfonamide or pharmaceutically acceptable salt, method of synthesis and composition showing antitumor action. Reagent 1: compound of the formula (II) where Y - NCO-group. Reagent 2: compound of the formula (III) where X - -NCO or NH₂-group. Amount of an active component in composition is 5-500 mg per a single dose. Compound (I) inhibits tumor growth by 81-100%. Synthesized compound is used in oncology. EFFECT: improved method. 1 tbl, 4 cl