Compound, method for treating or preventing overactive bladder or urinary incontinence in an individual, pharmaceutical composition, and use of -n- 2- (3,4-dichlorophenyl) -4- 4- (2-oxo -piperidin-1-yl) piperidino butyl -n-methyl-2-fluorobenzamide or a pharmaceutically acceptable salt thereof

摘要

"COMPOUND, METHOD FOR TREATMENT OR PREVENTION OF SUPERTIVE BLADDER OR URINARY INCONTINENCE IN AN INDIVIDUAL, PHARMACEUTICAL COMPOSITION, AND, USE OF (S) -N- [2- (3,4-DICHLOROPHENY) -4- [4- (2- OXO-PIPERIDIN-1-IL) PIPERI DINO] BUTIL] -N-METHYL-2-FLUOROBENZAMIDE OR A PHARMACEUTICALLY ACCEPTABLE SALT OF THE SAME ". NK2R-binding compounds according to structural diagram (I) usable for the treatment or prevention of OAB or IU in mammals, particularly humans, are described wherein, in said compounds D, A, R 1, R 2 3 ^ and R ^ 4 ^ are as defined in the report. Pharmaceutically advantageous salts of the compounds, methods of using the compounds alone or in combination with other pharmacological agents, and pharmaceutical compositions usable in the practice of the methods of the invention are also described.