METHOD OF SYNTHESIS OF N-ETHYLHYDROXYLAMINE HYDROCHLORIDE AND METHOD OF SYNTHESIS OF N,O-BIS-(1,1-DIMETHYLETHOXY)CARBONYL-HYDROXYLAMINE

摘要

FIELD: organic chemistry and technology. SUBSTANCE: product: N-ethylhydroxylamine hydrochloride. Reagent 1: di-tert.-butyldicarbonate. Reaction conditions: at 10-60 C in the presence of inert solvent and base followed by ethylation of the synthesized N, O-bis-[(1,1-dimethylethoxy)carbonyl] -hydroxylamine and further treatment of the obtained product with HCl. Synthesized compounds were used as semiproducts for synthesis of pharmaceutical preparations. EFFECT: improved method of synthesis. 10 cl