AGENT SHOWING INHIBITING EFFECT ON THE GROWTH AND METASTASING THE TRANSPLANTED TUMORS AND INHIBITING THE DEVELOPMENT OF CHEMICALLY INDUCED TUMORS

摘要

FIELD: medicine, oncology. SUBSTANCE: administration of fir coniferous needles aqueous extract to mice (C57BL/6) orally for 18 days inhibits the growth of transplanted malignant tumor of Lewis lung carcinoma by 47-66% and metastasing by 79%. Administration of preparation to mice CBA for 15 days increases the mean latent period time of chemically induced tumors appearance up to 167.0 ± 9.5 days as compared with 130.3 + 7.5 days in control group of animals. EFFECT: enhanced effectiveness of inhibition and prevention of tumors.