Method of synthesis of new compounds disaccharide, without the glycoside junction, the products obtained by this process and their applications as surfactant, or chelating agent.

摘要

We have prepared new disaccharide compounds associating, without any glycoside link, two derivatives of oses or of itols A and B, on sites chosen in advance of formula I: IMAGE The process for the synthesis of these compounds includes especially the stage of linking the units A and B by attack of a derivative of the unit B, in alcoholate form, on an anhydro group derived from the unit A. The products obtained bear, respectively, 0 to 3 ZIFI groups on the unit A and 0 to 3 ZJGJ groups on the unit B, as well as a modulable number of free OH groups which can vary from 0 to 4 (p) on the unit A and from 0 to 4 (p') on the unit B. The units A and B may create a second link by internal cyclisation. One of the groups ZIFI or ZJGJ may be a third unit C analogous to A and B, resulting in trisaccharide compounds. In addition, if the unit C is joined to B, it may also create a link with A by internal cyclisation and if the unit C is joined to A, it may also create a link with B by internal cyclisation. The surface-active, chelating and biological properties revealed by the products obtained are described with a view to applications as surface and/or chelating agents, calcium antagonist medications and antitumour medications.