首页> 外国专利> Process for the enzymatic production of isomerically pure isosorbide-2 and 5-monoesters as well as their conversion into isosorbide- 2- and 5- nitrate

Process for the enzymatic production of isomerically pure isosorbide-2 and 5-monoesters as well as their conversion into isosorbide- 2- and 5- nitrate

机译:酶法生产异构纯的异山梨醇2和5单酯以及将其转化为异山梨醇2-和5-硝酸盐的方法

摘要

Process for the enzymatic production of isomerically pure compounds having the general formulae I and II ##STR1## in which the substituents R have the meanings stated in the claims, as well as their use for the production of isomerically pure isosorbide-2-nitrate having the formula V and isosorbide-5-nitrate having the formula VI, ##STR2## which are both important as therapeutic agents for coronary diseases.
机译:酶法生产具有通式I和II的异构体纯化合物的方法,以及其中的取代基R具有权利要求中所述的含义,及其在制备异构体纯的异山梨醇-2-硝酸盐中的用途具有式V的化合物和具有式VI的5-硝酸异山梨酯,## STR2 ##对于冠心病都是重要的治疗剂。

著录项

  • 公开/公告号US5614643A

    专利类型

  • 公开/公告日1997-03-25

    原文格式PDF

  • 申请/专利权人 BOEHRINGER MANNHEIM GMBH;

    申请/专利号US19950481915

  • 发明设计人 MANFRED SCHNEIDER;ROBERT SEEMAYER;

    申请日1995-06-07

  • 分类号C07D493/00;

  • 国家 US

  • 入库时间 2022-08-22 03:10:22

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