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Phosphacan: a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell adhesion molecules
Phosphacan: a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell adhesion molecules
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机译:Phosphacan:与神经元和神经细胞粘附分子相互作用的大脑的硫酸软骨素蛋白聚糖
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摘要
A phosphacan proteoglycan molecule, or a functional derivatives thereof, binds to brain cells and to a number of cell adhesion molecules including Ng-CAM and N-CAM. Such proteoglycan molecules or functional derivatives, as well as nucleic acids coding therefore are useful in treating a subject having a disorder associated with conditions where it is desirable to promote nerve regeneration. The compositions and methods of the present invention are also useful for diagnosing and monitoring human tumors such as gliomas and astrocytomas.
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