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Amyloid precursor proteins and method of using same to assess agents which down-regulate formation of -amyloid peptide
Amyloid precursor proteins and method of using same to assess agents which down-regulate formation of -amyloid peptide
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机译:淀粉样前体蛋白及其用于评估下调淀粉样肽形成的试剂的方法
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摘要
This application describes a purified and isolated fragment of a nucleic acid molecule encoding an amyloid precursor mutein, wherein the fragment comprises a nucleic acid sequence encoding at least one marker and a nucleic acid sequence of about 419, about 475 or about 494 amino acid residues in which a portion thereof encodes a -amyloid protein domain. Also described is a method for screening for a compound which reduces the formation of -amyloid protein.
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