Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics

摘要

Diaromatic compounds, characterised in that they correspond to the following general formula: ##STR1## in which: R.sub.1 is --CH.sub.3, - -CH. sub.2 OH, --COR.sub.8 or --CH.sub.2 OCOR.sub.9, R.sub.8 is H, OH, -- OR. sub.10, --N(rr') or alkyl, R.sub.10 is alkyl, alkenyl, aryl or aralkyl, r and r' being H, alkyl, aryl, aralkyl, etc., r and r' together form a heterocycle, R.sub.9 is alkyl, alkenyl or a sugar residue, R.sub.2 and R. sub.3 are --OR.sub.11 or --OCOR.sub.11, R.sub.11 is H, alkyl, fluoroalkyl, aryl or aralkyl, R.sub.3 in addition being H, R.sub.4 is H, OH, alkyl, alkoxy, F, Cl or --CF.sub.3, R.sub.5 and R.sub.7 are H, OH, alkoxy, . alpha.-substituted alkyl or ,'-disubstituted alkyl, etc., R. sub.6 is H, OH, alkyl, alkoxy, cycloalkyl, etc., R.sub.5 and R. sub.7 cannot simultaneously be OH or alkoxy and R.sub.4, R.sub.5, R.sub.6 and R. sub.7 cannot simultaneously be H, R.sub.5 and R.sub.6 or R.sub.6 and R. sub.7 can form, with the aromatic ring, a ring with 5 or 6 members, X is chosen from amongst:PP(i) --C(R.sub.13 R.sub.14)-- C(R.sub. 16 R.sub.18)--W--, (ii) --C(R.sub.14)--W--R.sub.16 C(R.sub.18 R. sub.19)--, (iii) --C(R.sub.13 R.sub.14)--C(R.sub.15 R.sub.16)--C(R.sub.18 R.sub.20)- -, (iv) --CR.sub.17 CR.sub.21 --C(R.sub.13 R.sub.14)-- P Pin which:PPW is O, --NR.sub.12 or S(O). sub.n, n=0, 1 or 2, R.sub.13, R.sub.15 and R.sub.20 are H, --OR.sub.11, -- OCOR.sub.11 etc., R.sub.14, R.sub.16, R.sub.18 and R.sub.19 are H, aralkyl, alkyl, etc., when X is (i) R.sub.13 and R.sub.14 can form N--OR.sub.11 or . dbd.N--OCOR.sub.11, when X is (iii) or (iv), R.sub.14, R.sub.16 and R.sub. 18 are also --OR.sub.11 or --OCOR.sub.11, or R.sub.13, R.sub.14 or R.sub. 15, R.sub.16 taken together can form NOR.sub.11 or N--OCOR.sub. 11, R.sub.12 is H, alkyl, aralkyl, alkenyl, alkynyl or fluoroalkyl, R.sub. 17 is H, hydroxyl, alkyl or alkoxy, R.sub.21 is H or alkyl, and the salts of the compounds of formula (I).