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Conotoxin (conotoxin) peptide

机译:芋螺毒素

摘要

At the 3 'untranslated region and signal chain of genes encoding, (57) [summary] The present invention, conotoxin is a conotoxin peptide having a strong homology to the chain of α- conotoxin peptide within the A- pedigree It is directed to a peptide. The α- conotoxin peptide discussed further below, this peptide toxin of A- pedigree encompasses and α- conotoxin-like peptide κ- conotoxin peptide. α- conotoxin Pebuchido to share the motif chain "nuclear" in general. It is named α3 ​​/ 5 nucleus, this nuclear chain, Cys-Cys-Xaa-Xaa-Xaa-Cys-Xaa-Xaa-Xaa-Xaa-Xaa-Cys (consistent identification number: 1) is represented by. The nuclear chain share named etc. α4 / 7 nuclear in general, α- conotoxin-like peptide, Cys-Cys-Xaa-Xaa-Xaa-Xaa-Cys-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Cys can be expressed by: (2 consistent identification number). and a nuclear chain named κ7 / 2/1/3 nuclear in general, κ- conotoxin peptide, Cys-Cys-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Cys-Xaa-Xaa-Cys can be expressed by: (3 consistently identification number) -Xaa-Cys-Xaa-Xaa-Xaa-Cys.
机译:在编码(57)的基因的3'非翻译区和信号链上,[摘要]本发明的芋螺毒素是与A谱系中的α-芋螺毒素肽链具有很强同源性的芋螺毒素肽。肽。 α-芋螺毒素肽在下文进一步讨论,该A-谱系的肽毒素包括α-芋螺毒素样肽κ-芋螺毒素肽。通常,α-芋螺毒素Pebuchido共享基序链“核”。它被命名为α3/ 5核,该核链由Cys-Cys-Xaa-Xaa-Xaa-Cys-Xaa-Xaa-Xaa-Xaa-Xaa-Cys表示(一致标识号:1)。核链共享命名等。一般而言,α4/ 7核,类α-芋螺毒素,Cys-Cys-Xaa-Xaa-Xaa-Xaa-Cys-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Cys可以表示为:(2个一致的标识号)。并且通常称为κ7/ 2/1/3核的核链,可以表达κ-毒素肽Cys-Cys-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Cys-Xaa-Xaa-Cys :(3个一致的标识号)-Xaa-Cys-Xaa-Xaa-Xaa-Cys。

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