For diagnosing the Alzheimer's disease being joint, heredity indicator character, and diagnostic manner and the kit which are used

摘要

PCT No. PCT/FR95/00259 Sec. 371 Date Jan. 2, 1997 Sec. 102(e) Date Jan. 2, 1997 PCT Filed Mar. 6, 1995 PCT Pub. No. WO95/24504 PCT Pub. Date Sep. 15, 1995Combined use of at least two genetic markers selected from apolipoprotein E, D19S178 and apolipoprotein CII, for the diagnosis of Alzheimer's disease, especially apolipoprotein epsilon 4, long apolipoprotein CII (30+/-3 repeat patterns (CA) and short D19S178 (less than 167+/-4 nucleotides) alleles. The invention also concerns a method for the diagnosis of Alzheimer's disease and a kit for carrying out said method.