The manner which inhibits the breeding of the culture of the lactobacillus, dissolves the said bacterial cell with desire and application of the bacteriolysis culture which is obtained

摘要

(57) Abstract This invention, the product which includes manner or the said culture which obstructs the breeding of the lactobacillus culture, for example offers the cheese product, the said manner produces holin which can be obtained from the bacteriophage of the gram positive bacteriums and the bacteriophage of the especially lactobacillus in inside the cell of the lactobacillus, with in, situ as for the gene which said holin the code is done is under controlling the first adjustment promotor, as for said holin, it is possible, to show bacteriostatic operation, vis-a-vis the cell where it is produced by the system which is that with that, the nature production of the self lytic enzyme desirably without impairing, bores the hole through the cell membraneIt can do thing. It is desirable, furthermore, inside the cell of the lactobacillus, the lactobacillus or the dissolved element which can be obtained from that bacteriophage is produced, in situ as for the gene which the said dissolved element the code is done is under controlling the second adjustment promotor, the dissolved element which is produced with that, does the dissolution of the cell of the lactobacillus. The second adjustment promotor may be the same as the first adjustment promotor, the gene which holin and the dissolved element the code is done each, can place under the same adjustment promotor in one operon. It is desirable, as for the promotor, it is possible to regulate with the food class component or parameter. You can list the improvement of storage life of the product which depends on using the production and the bacteriolysis culture of the blend of the peptide which becomes deformed as other application of this invention, by the peptidase which separates after the bacteriolysis as the bactericide for the harmful bacterium or the pathogenic bacterium includes the bacteriolysis culture.