Optically active amine-boron compound, asymmetric reducing agent containing the same as an active ingredient, and method for producing optically active compound using the same

摘要

Optically active hydroxybenzylamine derivatives of the Formula: CHEM wherein R1 denotes a hydrogen atom, lower alkyl group or lower alkoxy group; R2 denotes a lower alkyl group; * signifies an asymmetric carbon atom; and the hydroxyl group is located on the phenyl at the ortho- or meta- position relative to the substituent having the asymmetric carbon, an optically active amine-boron compound having said derivative as a ligand, and a process for producing an optically active compound by using said compound. The derivations are useful as asymmetric ligands of asymmetric reducing agents. The optically-active amine-boron complex enables optically active products to be obtained specifically.