High sensitivity analysis null of density in blood of haroperidoru

摘要

PURPOSE:To analyze the halopellidols contained in blood by a simple pretreatment with high sensitivity by preparing a serum sample contg. the halopellidols to alkalinity, then extracting the sample with an org. solvent and analyzing the sample with gas chromatograph. CONSTITUTION:The halopellidols are determined by preparing the serum sample contg. the halopellidols to alkalinity, then extracting the sample with the org. solvent, analyzing the extracted liquid with the gas chromatograph provided with a chemically bonded and fused silica capillary column and detecting the separated components obtd. in such a manner with a surface ionization detector. The volume of the serum to be sampled is confined to about several 100mul. The pretreatment is executed by preparing the sampled serum to the alkalinity, then extracting the same at least once with the org. solvent. The org. solvent is used in approximately the same volume as the volume of the sampled serum in this case. The extracted liquid obtd. by this extraction can be usually analyzed with the gas chromatograph as it is and the use of this liquid after thickening at need is equally good.