Compound inhibitors of microsomal triglyceride transfer protein process to prevent and Treat atherosclerosis and / or reduce them to the blood serum triglyceride cholesterol and LipidsProcess for preparing Intermediates of said compounds and implementation procedure

摘要

These inhibitors of microsomal triglyceride transfer protein corresponding to the formulas (i), where X is a Group chr8, (ii); R8, R9 and R10 are independently alkylSaturated or aryl or arylalkyl, Het, eroarilo, heteroarilalquilo, cycloalkyl or cicloalquilalquilo,R1 is a group of fluorenilo type or of the type that may have indenilo Condensed Heterocyclic 5 to 6 elements and their corresponding n-oxides YQ is a co - or - SO2 Group.Also proposes a procedure for preparing such Compounds, inhibitors and Intermediates for the synthesis of the same.