Polypeptides useful for Detecting and / or treat infestations with T.Cruzi made with these polypeptides, Pharmaceutical compositions including these polypeptides; equipment for the diagnosis of such Infections, DNACells transformed with said Vectors and recombinant DNA.

摘要

These are new peptides for treating and / or detecting infestations with T. Cruzi, characterized in that they comprise at least 7 consecutive remains of the fraction SEQ ID NO: 1 between the lysine at rest 137 and the alanine at rest 247, or antigenic variants of the same, which differ only in substitutions or conservative modifications,The condition is that the polypeptide does not contain more than five consecutive residues of SEQ ID part 136: 1 between elamino acid 1 and elamino acid 136. In addition, the drug synthesis and diagnostic equipment for this infectious disease were also proposed. In addition, it also includes vector transformed cells, including Dnepr reaction to the polypeptide.