Platelet aggregation Inhibitors, their use in the manufacture of Medicines, Pharmaceutical composition containing them and Process for the preparation of these inhibitors

摘要

The compounds of the formula (i) where B is or CH2; X is selected from alkyl SR1 and NR1 R2, C1 - C7 SR1 is selected; and,Nr1r2 alkyl and R1 and C1 - C7; r2es each independently selected from C1 - C7 h, alkyl, optionally substituted eno Chain within the rent by one or more of o, S,N or Halogen; R3 and R4 are both R3 and R4 h, or together form a Link; it is COOH, C (o) NH (CH2 COOH) P, C (o) n] 2 [ch2qcooh; C (OR) nhch (COOH) CH2 COOH), or 5 - tetrazolil, where P,Q are each eindependien Dently yr 1, 2 or 3; and pharmaceutically acceptable Salts and prodrugs, Process for its preparationPharmaceutical compositions comprising the novel compounds and the use of the compounds in the manufacture of icamentos Med.In addition, within the link of the invention are new intermediaries for exclusive use in the procedure of obtaining the New Compounds.The New Compounds Arein particular useful for Prevention of aggregate D and platelets.