Processes to inhibit the growth of mammalian cells and the assembly of microtubules and to treat a disease that responds to inhibition of mitosis and pharmaceutical composition

摘要

A method for inhibiting mammalian cell growth is disclosed. The method uses compounds known as N-acetonylarylamides. The compounds have been shown to inhibit cell mitosis and to inhibit microtubule assembly. The method may be used to treat diseases associated with rapid cell growth, particularly cancer. The compounds used in the method of the present invention may be used in combination with other therapies and may be administered by known techniques for drug administration.