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HETEROCYCLIC DERIVATIVES WITH INDOLINE, INDOLE OR TETRAHYDROQUINOLINE CYCLE AND THEIR PHARMACEUTICAL USE
HETEROCYCLIC DERIVATIVES WITH INDOLINE, INDOLE OR TETRAHYDROQUINOLINE CYCLE AND THEIR PHARMACEUTICAL USE
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机译:具有二氢吲哚,吲哚或四氢喹啉循环的杂环衍生物及其医药用途
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摘要
A heterocyclic derivative of the formula (I) CHEM wherein each symbol is as defined in the specification, and pharmaceutically acceptable salts thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof exhibit superior ACAT inhibitory activity and lipoperoxidation inhibitory activity in mammals, and are useful as ACAT inhibitors and lipoperoxidation inhibitors. Specifically, they are useful for the prophylaxis and treatment of arteriosclerosis, hyperlipemia, arteriosclerosis in diabetes, and cerebrovascular and cardiovascular ischemic diseases.
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