Surfactant mammalian alveolar (mammalian ASP), recombinant DNA, encoding such an ASP, lung surfactant protein encoded by such a DNA, recombinant expression system comprising such a DNA, recombinant host cell transformed with a Such expression system, process for the preparation of mammalian ASP'et using such a cell and ASP frems

摘要

The complete coding sequences and amino acid sequences for both canine and human alveolar surfactant protein (ASP) are disclosed. Methods and vectors for obtaining these proteins in recombinant form are described. The availability of large amounts of these proteins through recombinant techniques permits the use of ASP in suitable pharmaceutical compositions in the treatment of respiratory deficiency syndromes.