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Transdermal drug delivery systems using sorbitan esters to improve skin permeability
Transdermal drug delivery systems using sorbitan esters to improve skin permeability
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机译:使用脱水山梨糖醇酯改善皮肤通透性的透皮给药系统
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摘要
Transdermal delivery systems for delivery of nitroglycerin are disclosed which deliver the drug at enhanced transdermal fluxes. The systems include, in addition to nitroglycerin, a permeation enhancer which is either a sorbitan ester, a C8-C22 aliphatic alcohol, or a mixture thereof. Methods for administering nitroglycerin using such permeation enhancers are also disclosed.
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