NEW PYRIMIDO (1,2-A) INDOLES

摘要

PyrimidoÄ1,2-aÜindole compounds of formula (I) and their isomers and salts are claimed. A,D,E,G,L,M = H, halo, CF3, CO2H, OH, 1-6C alkoxy, 1-6C alkoxycarbonyl or 1-6C alkyl optionally substituted by OH or 1-4C alkoxy; R1, R2 = H, 3-8C cycloalkyl or 1-10C alkyl (optionally substituted by 3-6C cycloalkyl) or phenyl; or R1 + R2 = 4-8C cycloalkyl; R3 = phenyl (optionally substituted by 1-3 NO2, CO2H, halo, CN, 2-6C alkenyl or alkoxycarbonyl or 1-6C alkyl (itself optionally substituted by OH, CO2H or 1-6C alkoxy or alkoxycarbonyl), or by one OR4 or NR5R6); R4 = H or 1-6C alkyl or alkenyl; R5, R6 = phenyl, H or 1-6C alkyl, or 1-8C acyl optionally substituted by NR7R8; R7, R8 = H or 1-8C acyl.