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PROCESS FOR PRODUCING PHARMACEUTICAL COMPOSITION CONTAINING IMMUNOGLOBULIN A, IMMUNOGLOBULIN B AND TRANSFERINE, AND THE ACTIVE COMPONENTS
PROCESS FOR PRODUCING PHARMACEUTICAL COMPOSITION CONTAINING IMMUNOGLOBULIN A, IMMUNOGLOBULIN B AND TRANSFERINE, AND THE ACTIVE COMPONENTS
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机译:制备包含免疫球蛋白A,免疫球蛋白B和转铁蛋白以及活性成分的药物组合物的方法
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摘要
(57) EXTRACT The present invention provides a plasma protein enhanced pharmaceutical antimicrobial, antitussive, and antiallergic pharmaceutical composition of 0.40-0.80 parts by weight of IgG and 0.15 parts by weight of heat atoms and 1 parts thereof. 0.45 parts by weight of transferrin, optionally inactivated and / or eliminated by the presence of infectious agents, is mixed with one or more known auxiliaries and / or excipients and formulated into a pharmaceutical formulation. The present invention further relates to a novel process for the preparation of active ingredients of a composition by heat-contacting a plasma fraction or plasma containing IgA, IgG and transferrin, if necessary, after inactivation and / or removal of any infectious agents present in an anion exchanger. , IgG and transferrin are mass-eluted in known manner, the precursor is separated from unwanted accompanying proteins, and IgA, IgG, and transferrin from precipitated, purified IgA, IgG and transferrin-containing cultures are precipitated, precipitated IgA, IgG esterferrin is released, lyophilized, and then activated by the infectious catabolism. ŕ
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