PROCESS FOR PRODUCING ISOMER MIXTURES COMPOSED OF O-PHENOXYALKYLHYDROXYL AMINES OR O-PHENOXYALKYLOXIMES AND THE ISOMER MIXTURES

摘要

The present invention relates to a process for the preparation of O- (phenoxyalkyl) hydroxyamines of the general formulas (Ia) and (Ib) or to the O- (phenoxyalkyl) oximes of the general formula (VIa) and (VIb), of which R1 is an alkyl tube; R2 is alkyl; R3 is alkyl or alkoxy, or R2 and R3 together with the carbon atom form an isocyclic ring; Ar optionally substituted phenyl tube - for the preparation of isomer mixtures and the corresponding salt mixtures. Compounds of formula (Ia) and (Ib) are prepared by a) mixing a isomeric mixture of O- (2-hydroxyethyl) oximes of formula (IIa) and (IIb) in the presence of a base with a methylphenyl of formula (III). -halogenide - of which R4 is an organic tube; Fish is a fish gene - it is reacted into the corresponding parent compound of formula (IVa) and (IVb); and b) reacting this mixture, optionally without isolation, in the presence of a base with a phenolic derivative of the general formula (V) to give a mixture of O- (phenoxyalkyl) oxymes of the general formula (VIa) and (VIb), and then c) it is hydrolysed with an acid and, if desired, d) the compounds of the formulas (Ia) and (Ib) are liberated from the salts thus formed by means of a base. ŕ