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THE COMBINATION OF GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR, FOR TREATING CONGESTIVE HEART FAILURE.
THE COMBINATION OF GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR, FOR TREATING CONGESTIVE HEART FAILURE.
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机译:生长激素和胰岛素样生长因子的组合,用于治疗慢性心力衰竭。
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摘要
Methods of enhancing myocardial contractility and cardiac performance in a mammal with congestive heart failure are disclosed. In a first method a mammal with congestive heart failure is treated by administering to the mammal an effective amount of a combination of growth hormone (GH) and insulin-like growth factor (IGF-I). A second method comprises administering to the mammal an effective amount of a combination of GH and IGF-I in the presence of an ACE inhibitor. This method results in enhancement of myocardial contractility and cardiac performance above the level achieved with ACE inhibition alone. Preferably the mammal is a human.
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