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USE OF BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN IN TREATING GRAM-NEGATIVE BACTERIAL INFECTION
USE OF BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN IN TREATING GRAM-NEGATIVE BACTERIAL INFECTION
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机译:细菌/通透性增加蛋白在治疗革兰氏阴性细菌感染中的应用
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摘要
The present invention relates to methods and compositions for treating gram-negative bacterial infections, using BPI protein products. Co-treatment, or concurrent administration, of BPI protein product with an antibiotic in treatment of gram-negative bacterial infections improves the therapeutic effectiveness of the antibiotic, including increasing antibiotic susceptibility of gram-negative bacteria and reversing resistance of the bacteria to antibiotics.
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