首页> 外国专利> BIOLOGICALLY ACTIVE AGENT EXHIBITING IMMUNOMODULATING PROPERTY, METHOD OF OBTAINING SAME, PREPARATION CONTAINING SUCH AGENT AND METHOD OF NORMALISING PHYSIOLOGICAL CONDITION OF HUMAN AND ANIMAL ORGANISMS BY USING SUCH PREPARATION

BIOLOGICALLY ACTIVE AGENT EXHIBITING IMMUNOMODULATING PROPERTY, METHOD OF OBTAINING SAME, PREPARATION CONTAINING SUCH AGENT AND METHOD OF NORMALISING PHYSIOLOGICAL CONDITION OF HUMAN AND ANIMAL ORGANISMS BY USING SUCH PREPARATION

机译:具有免疫调节特性的生物活性剂,获得该方法的方法,包含该试剂的制剂以及通过使用该制剂对人类和动物有机体的生理状况进行标准化的方法

摘要

A biologically active agent (BAA) is based on water-soluble products of hydrolysis of ingredients of disintegrated animal tissue which consist of organic substances, and has immunomodulating properties. The agent contains products of hydrolysis of morphoplasma components and of glycocalyx of cells (MCGC) modified during the processes of embryogenesis and/or proliferation and/or differentiation of cells, and/or during a pathology preceding or accompanying the process of regeneration and/or repatriation of the tissue. A method for obtaining BAA comprises disintegration of a washed raw material based on animal tissues, hydrolysis of the obtained ingredients with their subsequent centrifuging of the hydrolysis products or their filtration and separation of supernatant as desired product as the raw material animal tissues with modified MCGC are used. Before the hydrolysis the homogenization is carried out together with purification and elimination of non- disintegrated tissue elements and the supernatant is extracted containing ingredients with modified MCGC. A pharmaceutical preparation for normalization of physiological state of human beings and animals based on organic substances-products of hydrolysis of ingredients of animal tissue comprises, as active agent, BAA which contains among the hydrolysis products with modified MCGC organic substances at the following ratio in per cent by weight: polypeptides up to 26.0, peptides 10.0-23.0, amino acids 32.0-66.1, carbonhydrates 10.5-23.5, lipids, nucleotides and other organic substances 2.0-11.0 with the content of BAA in the preparation equal to 0.001-85.0 % by weight, the balance consisting of a solvent.
机译:生物活性剂(BAA)是基于由有机物质组成的分解的动物组织的成分水解而成的水溶性产物,具有免疫调节特性。该试剂包含在胚发生和/或细胞增殖和/或分化过程中,和/或在再生和/或过程之前或伴随的病理过程中,修饰的细胞质浆成分和糖萼的水解产物(MCGC)。遣返组织。获得BAA的方法包括基于动物组织的洗涤的原料的分解,所获得的成分的水解,随后的水解产物的离心或它们的过滤和上清液的分离,将所需产物作为具有改性MCGC的原料动物组织。用过的。在水解之前,进行均质化,同时纯化和消除未崩解的组织成分,并提取上清液,其中含有经修饰的MCGC的成分。基于有机物质-动物组织成分的水解产物,用于使人和动物的生理状态正常化的药物制剂,包含BAA作为活性剂,所述BAA在水解产物中含有改性MCGC有机物质,其比例为重量百分比:最多26.0的多肽,肽10.0-23.0,氨基酸32.0-66.1,水合物10.5-23.5,脂质,核苷酸和其他有机物质2.0-11.0,制剂中BAA的含量等于0.001-85.0%重量,其余部分由溶剂组成。

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