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Protein recognized by antibodies raised against native P28 of schitosoma mansoni.

机译:被抗曼氏血吸虫天然P28的抗体识别的蛋白质。

摘要

The invention is aimed at developing a vaccine against schistosomosis. It relates to a protein comprising the epitopes of the protein p28, a poxvirus comprising a gene coding for the said protein, a cell incorporating an expression vector of the said protein, a process for the preparation of the said protein, a DNA sequence coding for the protein p28, a pharmaceutical composition, antibodies put up against the said protein and their application as diagnostic agents for schistosomosis. The invention also relates to the application of the said protein as an agent exhibiting a glutathion-S-transferase activity.
机译:本发明旨在开发抗血吸虫病的疫苗。本发明涉及包含蛋白p28的表位的蛋白,包含编码该蛋白的基因的痘病毒,掺入该蛋白表达载体的细胞,该蛋白的制备方法,编码该蛋白的DNA序列。蛋白p28,一种药物组合物,针对所述蛋白的抗体及其在血吸虫病诊断试剂中的应用。本发明还涉及所述蛋白质作为具有谷胱甘肽-S-转移酶活性的试剂的用途。

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