首页> 外国专利> Monoaceticos derived peptide leu-phe-ala and ala-leu-phe and its use in identifying and destroying tumor cells and virus-infected cells.

Monoaceticos derived peptide leu-phe-ala and ala-leu-phe and its use in identifying and destroying tumor cells and virus-infected cells.

机译:单乙酸衍生肽leu-phe-ala和ala-leu-phe及其在鉴定和破坏肿瘤细胞和病毒感染细胞中的用途。

摘要

DERIVATIVES MONOACETICOS tripeptide leucine-FENILALANINAALANINA and alanine-Leucine-Phenylalanine is effective to activate NK cells to identify and destroy DIRECTLY THAT IS INTERFERENCE BY THE IMMUNE CELLS TUMOR ABNORMAL cells metastatic, viruses and cells carrying SYSTEM virus, which results in a "Immunotherapy ACTIVE". The invention also relates to use of said tripeptide monoacetyl for the treatment and prophylaxis of cancer and viral diseases, as well as pharmaceutical compositions containing one or both compounds ABOVE, together with a suitable carrier and, optionally, AFTER SUBSTANCES pharmaceutically active.
机译:衍生品MONOACETICOS三肽亮氨酸-FENILALANINAALANINA和丙氨酸-亮氨酸-苯丙氨酸可有效激活NK细胞,以直接识别和破坏免疫细胞的干扰,而肿瘤异常细胞则转移,感染病毒和携带系统病毒的细胞,从而导致“免疫治疗” 。本发明还涉及所述三肽单乙酰基在治疗和预防癌症和病毒性疾病中的用途,以及包含一种或两种以上化合物,以及合适的载体和任选的具有药物活性的物质之后的药物组合物。

著录项

  • 公开/公告号ES2119987T3

    专利类型

  • 公开/公告日1998-10-16

    原文格式PDF

  • 申请/专利权人 GRIPPA LEONIDA;

    申请/专利号ES19940830111T

  • 发明设计人 GRIPPA LEONIDA;

    申请日1994-03-16

  • 分类号C07K5/083;A61K38/06;

  • 国家 ES

  • 入库时间 2022-08-22 02:54:30

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