METHODS FOR THE MANUFACTURE OF AMORPHOUS CEFUROXIME AXETIL

摘要

A process for preparing pure amorphous cefuroxime axetil comprising the stepsof dissolving crystalline cefuroxime axetil in a highly polar organic solvent andadding the resulting solution to water, or alternatively, dissolving crystallinecefuroxime axetil in a highly polar solvent and adding small quantities of waterto the organic solution and adding the resulting organic-aqueous solution towater.