The present invention relates to Candida albicans proteins, such as CaCla4p,Cst20p, CaCdc42p and CaBemlp, associated with virulence and hyphal formationand uses thereof, such as to design screening tests for inhibitors for thetreatment of pathogenic fungi infections and/or inflammation conditions. Theinvention also relates to an in vitro screening test for compounds to inhibitthe biological activity of at least one protein selected from the groupconsisting of CaCla4p, Cst20p, CaCdc42p and CaBemlp, which comprises: a) atleast one of said proteins; and b) means to monitor the biological activity ofsaid at least one protein; thereby compounds are tested for their inhibitingpotential.
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