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(dape) gene of (helicobacter pylori) and (dape)sup-/sup mutant strains of (helicobacter pylori)
(dape) gene of (helicobacter pylori) and (dape)sup-/sup mutant strains of (helicobacter pylori)
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机译:(幽门螺杆菌)的(dape)基因和(幽门螺杆菌)的(dape)- sup>突变株
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摘要
The invention provides the dapE gene of Helicobacter pylori and H. pylori dapE- mutants and to methods of using the mutants to express foreign genes and immunize against foreign agents. The dapE gene can consist of the nucleotide sequence defined in SEQ ID NO:3. Nucleic acids of the gidA gene and ORF 2 of H. pylori are provided. Examples of these nucleic acids can be found in SEQ ID NO:1 and SEQ ID NO:5, respectively. Having provided these nucleic acids, hybridizing nucleic acids in accord with the description of hybridizing nucleic acids of dapE are also provided.
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机译:本发明提供了幽门螺杆菌和幽门螺杆菌dapE-突变体的dapE基因,以及使用该突变体表达外源基因和针对外源试剂免疫的方法。 dapE基因可以由SEQ ID NO:3定义的核苷酸序列组成。提供了幽门螺杆菌的gidA基因和ORF 2的核酸。这些核酸的实例分别可见于SEQ ID NO:1和SEQ ID NO:5。提供了这些核酸之后,还提供了与dapE的杂交核酸的描述一致的杂交核酸。
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