A device (10) for holding the protective sheath (34) of at least one hypodermic needle (30) in a single-handed operation includes a hollow receptacle (12) formed with a cavity (14) which contains a deformable support material (24). The support material is penetrable by the sheath to embed the tip portion thereof in the support material and thereby hold the sheat in a substantially fixed position relative to the receptacle while the needle is withdrawn from or inserted into the sheath. The device also includes a contact adhesive (36) on its base surface to selectively attach the device to a solid object to stabilize the receptacle during use.
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