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PREVENTIVES AND/OR REMEDIES FOR DISEASES CAUSED BY ABNORMAL NEOVASCULARIZATION
PREVENTIVES AND/OR REMEDIES FOR DISEASES CAUSED BY ABNORMAL NEOVASCULARIZATION
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机译:异常神经囊化引起的疾病的预防和/或补救措施
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摘要
Drugs containing as the active ingredient substances selected from the group consisting of phenylacetic acid derivatives represented by general formula (I), their physiologically acceptable salts and hydrates, and solvates thereof. In said formula (I) R1 represents hydrogen or R5CO- (wherein R5 represents C¿1-6? alkyl or C¿6-10 aryl); R?2 and R3¿ independently represent each hydrogen or C¿1-4? alkyl; and R?4¿ represents hydrogen or C¿1-6? alkyl; and being useful in preventing and/or treating diseases caused by abnormal neovascularization such as cancer, rheumatoid arthritis, atherosclerosis, diabetic retinitis, hemangioma, psoriasis, etc.
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机译:含有选自通式(I)表示的苯乙酸衍生物,其生理上可接受的盐和水合物及其溶剂化物的物质作为活性成分的药物。在上述式(I)中,R1代表氢或R5CO-(其中R5代表C1-6烷基或C-6-10芳基); R 2和R 3独立地代表氢或C 1-4。烷基; R 4代表氢或C 1-6。烷基;并且可用于预防和/或治疗由异常新血管形成引起的疾病,例如癌症,类风湿性关节炎,动脉粥样硬化,糖尿病性视网膜炎,血管瘤,牛皮癣等。
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