Polyamines and polypeptides useful as antagonists of excitatory amino acid neurotransmitters and/or blockers of calcium channels

摘要

This invention relates to certain polypeptides found to be present in the venom of the Agelenopsisaperta spider. The polypeptides block calcium channels in cells of various organisms and are useful in blocking said calcium channels in cells, per se, in the treatment of calcium channel mediated diseases and conditions and in the control of invertebrate pests.