INHIBITION OF APOPTOSIS IN CELLS EXPRESSING FAS-LIGAND FOLLOWING ACTIVATION

摘要

Method for mediating the expression by mammalian cells of Fas-Ligand following activation using retinoid compounds, and specifically retinoid compounds which activate both retinoid X receptors and retinoic acid receptors. Examples of such retinoid compounds are 9-cis retinoic acid and related compounds. The method provides a means for inhibiting apoptosis in cells which express Fas-Ligand following activation.