16-Membered macrolide derivative having sustained antibacterial activity in plasma, synthesis intermediate thereof and process for producing the same

摘要

A compound represented by the formula (I): wherein R¹ represents a hydroxyl group and a hydrogen atom or a group of the formula OCOR⁶, wherein R⁶ represents a straight chain alkyl group having 1 to 3 carbon atoms, and a hydrogen atom, R² represents a hydrogen atom or a group of the formula COR⁶, wherein R⁶ is as defined above, R³ represents a hydrogen atom or a group of COR⁶, wherein R⁶ is as defined above, R⁴ represents a straight chain alkyl group having 1 to 4 carbon atoms, and R⁵ represents a substituted or unsubstituted straight chain or branched alkyl or aralkyl group having 1 to 10 carbon atoms, or a pharmaceutically acceptable salt thereof.