Three benzopyranocoumarins(OBH, OMH and ODH) were synthesized and characterized via IR, 1H NMR and HRMS. The HB energy in OBH, OMH and ODH was performed with the density functional theory(DFT) [B3LYP/6-31G*] method. The in vitro antibacterial activity of OBH, OMH and ODH against drug-sensitive S. aureus(S. aureus ATCC 29213) strain, MRSA strain(MRSA XJ 75302), drug-sensitive S. epidermidis strain(S. epidermidis ATCC 14990) and methicillin-resistant S. epidermidis strain(MRSE XJ 75284) was evaluated by observing the minimum inhibitory concentration. The results showed that among the three compounds, ODH exhibited the most potent antibacterial activity.
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机译:Design, Synthesis and Characterization of Novel Sulfonamides Derivatives as Anticancer Agent Targeting EGFR TK, and Development of New Methods of Synthesis by Microwave Irradiation
机译:studies on asymmetric syntheses of Benzophenanthridine alkaloids and the Related spiro Compounds: studies on Chelidonine synthesis and Total synthesis of arnottins I and II