Monoclonal antibodies against hepatitis B virus X protein, hybridoma cell lines producing the same, and methods for producing them

摘要

The present invention relates to a monoclonal antibody against X protein, which is presumed to be directly involved in the mechanism of HBV-induced hepatitis transfer into hepatocellular carcinoma as a regulatory protein among four proteins constituting hepatitis B virus, a hybridoma cell line The monoclonal antibody of the present invention is excellent in antigen specificity and can be effectively used for diagnosing liver cancer caused by hepatitis virus and developing anticancer drugs by measuring the level of X protein in blood.