The present invention relates to a water-soluble extract of Asian ticoside and macesacoside and a method for separating the same from Centella asiatica (L) Urb, which has excellent hepatocyte protective effect and anti-fibrosis effect.;Methylene chloride was added to the extract to obtain a sample. The extract was extracted with normal butane in the supernatant. The n-butane layer was washed with caustic soda and washed with water. The butanol layer was concentrated under reduced pressure and crystallized by addition of ethyl acetate, followed by separation, washing, and drying to separate an extract of the mixture of the Asian ticoside and the macacaside.;In order to confirm the protective effect of hepatocyte by the water-soluble extract, toxicity and toxicity of hepatocyte were induced by 40 ~ 60% It was confirmed that the effect of mitigation of fibrosis was confirmed through the fiberization experiment.
展开▼
