首页> 外国专利> AKLAVINONE 11-HYDROXYLASE, GENE CODING FOR ALKAVINONE 11-HYDROXYLASE, EXPRESSION VECTOR AND PROCESS OF HYBRID ANTIBIOTIC

AKLAVINONE 11-HYDROXYLASE, GENE CODING FOR ALKAVINONE 11-HYDROXYLASE, EXPRESSION VECTOR AND PROCESS OF HYBRID ANTIBIOTIC

机译:AKLAVINONE 11-羟化酶,ALKAVINONE 11-羟化酶的基因编码,杂交载体的表达载体和制备方法

摘要

The present invention provides a gene encoding aclabinone 11-hydroxylase, an expression vector comprising the same, and a host cell transformed with the expression vector, and also by expressing the gene in a cell, a hybrid anthracycline system Provided are methods for preparing antibiotics. Also provided is a novel antibiotic aclacinomycin X (2 ''-amino aclacinomycin Y) produced by wild-type strains and a method for preparing the same.
机译:本发明提供了编码Aclabinone 11-羟化酶的基因,包含该基因的表达载体和用该表达载体转化的宿主细胞,并且还通过在细胞中表达该基因,获得了蒽环类抗生素的杂种系统。提供了制备抗生素的方法。还提供了由野生型菌株产生的新型抗生素阿奇霉素X(2′-氨基阿奇霉素Y)及其制备方法。

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