The present invention provides a gene encoding aclabinone 11-hydroxylase, an expression vector comprising the same, and a host cell transformed with the expression vector, and also by expressing the gene in a cell, a hybrid anthracycline system Provided are methods for preparing antibiotics. Also provided is a novel antibiotic aclacinomycin X (2 ''-amino aclacinomycin Y) produced by wild-type strains and a method for preparing the same.
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