Title: Novel aryl isocyanide derivatives having inhibition of tyrosinase activity and inhibition of melanin biosynthesis and methods for producing the same

摘要

The present invention relates to a novel arylisocyanide derivative of the general formula (I) having a tyrosinase activity inhibiting activity and a process for producing the same.;Wherein R_OneAnd R₂Each independently represent hydrogen, methyl or methoxy, R₃And R₄R₃Is hydrogen, R₄C_One-C₄Alkoxycarbonyl C_One-C₄Alkyl, C_One-C₄Alkoxycarbonyl C₃-C₄Alkenyl, /RTI hydroxy or t-butyldimethylsilyloxy, C₃-C₅Alkoxy, hydroxy C₃-C₅Alkyl, or R₄Is hydrogen, R₃C_One-C₄Alkoxycarbonyl C_One-C₄Alkoxycarbonyl C₃-C₄Alkenyl, /RTI hydroxy or t-butyldimethylsilyloxy, C₃-C₅Alkoxy, hydroxy C₃-C₅Alkyl.