METHOD FOR PRODUCING HIGHLY ACTIVE ACETYLSALICYLIC ACID (ASPIRIN)

摘要

FIELD: chemopharmaceutic industry; production of drugs. SUBSTANCE: proposed method is based upon standard technology, but incorporates inventively novel feature, namely: step of mechanical treatment in mills- activators, in atmosphere having relative humidity 70- 100% until material reaches specific surface area 2.0-2.5 mg/g. Electric power 1-5 kWt/kg is applied to mills. EFFECT: 1) greater dissolution rate of acetylsalicylic acid (aspirin); 2) enhanced therapeutic activity, while preserving high degree of purity and compositional stability. 2 dwg