where R1 and R2 - are similar or different (C1-C4)-alkyl; R3-R4 is -O-; R4 is -S- or R4R5N where R4 - (C1-C4)-alkyl; R5 - hydrogen, (C1-C4)-alkyl or phenyl. Compounds are synthesized by cyclization reaction of cyanoimidate of the formula (II) with hydrogen halogen and pyrimidine halogen-derivative of the formula (III) is formed. The latter is reacted with compound of the formula (IV) M-R3 where R3= R4 is -O- or R4 is -S-; M - alkaline metal atom, or with alkylamine of the formula (V) and converted to the end compound of the formula (I). Also, 2-N-butylamino-4,6-dimethoxypyrimidine is described. Synthesized compounds are used as semiproducts for synthesis of herbicides. EFFECT: improved method of synthesis. 10 cl, 1 tbl"/>
METHOD OF SYNTHESIS OF 2-SUBSTITUTED 4,6-DIALKOXYPYRIMIDINES, 2-N-BUTYLAMINO-4,6-DIMETHOXYPYRIMIDINE AND A METHOD OF SYNTHESIS OF HALOGEN-DERIVATIVE OF PYRIMIDINE
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METHOD OF SYNTHESIS OF 2-SUBSTITUTED 4,6-DIALKOXYPYRIMIDINES, 2-N-BUTYLAMINO-4,6-DIMETHOXYPYRIMIDINE AND A METHOD OF SYNTHESIS OF HALOGEN-DERIVATIVE OF PYRIMIDINE
METHOD OF SYNTHESIS OF 2-SUBSTITUTED 4,6-DIALKOXYPYRIMIDINES, 2-N-BUTYLAMINO-4,6-DIMETHOXYPYRIMIDINE AND A METHOD OF SYNTHESIS OF HALOGEN-DERIVATIVE OF PYRIMIDINE
FIELD: organic chemistry and technology. SUBSTANCE: invention proposes a method of synthesis of 2-substituted 4,6-dialkoxypyrimidines of the formula (I) where R1 and R2 - are similar or different (C1-C4)-alkyl; R3-R4 is -O-; R4 is -S- or R4R5N where R4 - (C1-C4)-alkyl; R5 - hydrogen, (C1-C4)-alkyl or phenyl. Compounds are synthesized by cyclization reaction of cyanoimidate of the formula (II) with hydrogen halogen and pyrimidine halogen-derivative of the formula (III) is formed. The latter is reacted with compound of the formula (IV) M-R3 where R3= R4 is -O- or R4 is -S-; M - alkaline metal atom, or with alkylamine of the formula (V) and converted to the end compound of the formula (I). Also, 2-N-butylamino-4,6-dimethoxypyrimidine is described. Synthesized compounds are used as semiproducts for synthesis of herbicides. EFFECT: improved method of synthesis. 10 cl, 1 tbl
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机译：领域：有机化学和技术。物质：本发明提出了一种合成式（I）的2-取代的4,6-二烷氧基嘧啶的方法。<图像文件=“ 00000005.GIF” he =“ 28” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 30“ />，其中R 1 和R 2 -相似或不同（C 1 -C 4 ） -烷基; R 3 -R 4 是-O-; R 4 是-S-或R 4 R 5 N，其中R 4 -（C 1 -C 4 ）-烷基; R 5 -氢，（C 1 -C 4 ）-烷基或苯基。通过式（II）的氰基亚氨酸酯的环化反应合成化合物。<图像文件=“ 00000006.GIF” he =“ 24” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 30” />与氢卤素和嘧啶形成式（III）的卤素衍生物。<图像文件=“ 00000007.GIF” he =“ 28” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 30” />。后者与式（IV）的化合物MR 3 反应，其中R 3 = R 4 为-O-或R 4 是-S-; M-碱金属原子或具有式（V）的烷基胺并转换为式（I）的末端化合物。另外，描述了2-N-丁基氨基-4，6-二甲氧基嘧啶。合成的化合物用作合成除草剂的半成品。效果：改进的合成方法。 10厘升，1汤匙
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